- Build more muscle, less fat - Sustain high insulin sensitivity - Great to be taken with Creatine Power - Multi phase free radicals scavenger Alpha Lipoic Acid (ALA) helps to maintain insulin sensitivity. This is achieved by increasing the mobility of a specific but important type of insulin receptors (GLUT 4) by protecting them from excessive oxidation. This property made ALA valuable to weight trainers. In a mass gaining phase, increased calories intake is necessary to create anabolic/growth environment. Unfortunately with increased calories intake, insulin sensitivity tend to be blunted. The lower the insulin sensitivity, the more calories will be deposited into the fat cells rather than muscle cells: something not favourable to serious bodybuilders. About 100mg taken with the each meal works well. This is where ALA can be of value. ALA helps to sustain high insulin sensitivity. Increased insulin sensitivity means more nutrients are partitioned into the body compartment you want: the muscle cells rather than fat cells. Alpha Lipoic Acid (ALA) is also well known as "the universal anti-oxidant", meaning it is both water and fat soluble. It also serves as a universal anti-oxidant reenforcers when certain antioxidants in the body fall short. This formula is fortified with Biotin which is an essential cofactor of intracellular carboxylase enzymes and is important for energy production and lipid metabolism. Note: Individuals who are diabetic, being treated for serum glucose control, pregnant or lactating should consult a health care professional before using this product. Scientific References 1. Diabetes Care. 2006 Nov;29(11):2365-70. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Ziegler D et al. 2. Regul Toxicol Pharmacol. 2006 Oct;46(1):29-41. Epub 2006 Aug 14. Safety evaluation of alpha-lipoic acid (ALA). Cremer DR et al. 3. J Immunol. 2006 Aug 15;177(4):2630-7. Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. Schreibelt G et al. 4. Diabetes. 2006 Aug;55(8):2238-44. Alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet. Yi X & Maeda N. 5. J Nutr Biochem. 2003 May;14(5):288-94. Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. Maritim AC et al. 6. Free Radic Biol Med. 2006 Jan 1;40(1):3-12. Exercise training and the antioxidant alpha-lipoic acid in the treatment of insulin resistance and type 2 diabetes. Henriksen EJ. 7. Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E529-36. Epub 2004 Apr 6. Interactions of exercise training and alpha-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats. Saengsirisuwan V et al. 8. Metabolism. 2003 Sep;52(9):1167-74. Interactions of conjugated linoleic acid and lipoic acid on insulin action in the obese Zucker rat. Teachey MK et al. 9. Nutrition. 2001 Oct;17(10):888-95. Molecular aspects of lipoic acid in the prevention of diabetes complications. Packer L, Kraemer K, Rimbach G. 10. Free Radic Biol Med. 1995 Aug;19(2):227-50. Alpha-Lipoic acid as a biological antioxidant. Packer L, Witt EH, Tritschler HJ. 11. Diabetologia. 1999 Aug;42(8):949-57. Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. Rudich A et al. 12. Diabetes. 1998 Oct;47(10):1562-9. Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. Rudich A et al. 13. J Biol Chem. 1999 Apr 9;274(15):10595-602. Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. Tirosh A et al. |
Supplement Facts
Serving size: 1 Capsule
Servings Per Container: 180
Amount Per Serving
Biotin 333mcg
Alpha Lipoic Acid 100mg
(Thiotic Acid)
Other Ingredients: Rice powder and
magnesium stearate. Capsule consists of
gelatin, glycerin and water. Contains NO
common allergen.
Serving size: 1 Capsule
Servings Per Container: 180
Amount Per Serving
Biotin 333mcg
Alpha Lipoic Acid 100mg
(Thiotic Acid)
Other Ingredients: Rice powder and
magnesium stearate. Capsule consists of
gelatin, glycerin and water. Contains NO
common allergen.
| Jarrow's Formula's Alpha Lipoic Acid (ALA) 180 Caps 100mg per Cap Price: $49 |
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| New Bigger Size: Cos it's good stuff |