- Prevent metabolic slow down during dieting - Great addition to thermogenic formula Metabolic Thyrolean improves and maintains your metabolic rate when you restrict calories. In the thyroid, Metabolic Thyrolean improves the conversion of thyroid hormones to the more active hormones to keep metabolic rate fast . It also signals the liver of sufficient ATP so that the liver has will not go into a fat accumulating mode. In the brain, Metabolic Thyrolean increases the level of neurotransmitters that reduces the feeling of hunger. These result in the metabolism remaining elevated, with a positive effect on metabolism, calorie-burning and fat loss. One of things that make weight loss difficult is during a calories restricted phase there is a reduction in active thyroid hormone resulting in slow metabolic rate and a reduction of certain neurotransmitters that increase food intake. Gugglesterone, that preserve or increase thyroid output, preserve or increase the metabolic rate (without stimulants), and provides much needed substrates for the production of neurotransmitters (epinephrine and norepinephrine) involved in weight loss and metabolic rate. Gugglesterone therapy has been used in Traditional Indian Medicine system, Ayurveda to improve blood lipid profile. Some studies found that phosphate supplementation may also improve weight loss by supporting Thyroid hormones and metabolism. Phosphate supplemenation is useful for weight loss programs in the obese than those who are relatively lean. Two studies shown that acute phosphate addition to a meal increased thermogenesis in obese women, while one shown no such effect in lean women. Scientific References 1. J Physiol Pharmacol. 1993 Dec;44(4):425-40. Effect of phosphate supplementation on metabolic and neuroendocrine responses to exercise and oral glucose load in obese women during weight reduction. Kaciuba-Uscilko H, Nazar K, Chwalbinska-Moneta J, Ziemba A, Kruk B, Szczepanik J, Titow-Stupnicka E, Bicz B. 2. J Physiol Pharmacol. 1996 Jun;47(2):373-83. Phosphate supplementation prevents a decrease of triiodothyronine and increases resting metabolic rate during low energy diet. Nazar K, Kaciuba-Uscilko H, Szczepanik J, Zemba AW, Kruk B, Chwalbinska-Moneta J, Titow-Stupnicka E, Bicz B, Krotkiewski M. 3. Miner Electrolyte Metab. 1994;20(3):147-52. Increased postprandial energy expenditure in obese women after peroral K- and Mg-phosphate. Jaedig S, Lindgarde F, Arborelius M. 4. Int J Obes. 1991 Jun;15(6):429-36. Increased metabolic rate in obese women after ingestion of potassium, magnesium- and phosphate-enriched orange juice or injection of ephedrine. Jaedig S, Henningsen NC. 5. New triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resins, and their potent anti-inflammatory effect on adjuvant-induced air-pouch granuloma of mice. Bioorg Med Chem Lett 2001 Apr 23;11(8):985-9. Kimura I et. al. 6. Gugulu (Commiphora mukul) induces triiodothyronine production: possible involvement of lipid peroxidation. Life Sci 1999;65(12):PL137-41. Panda S, Kar A. 7. J Postgrad Med 1995 Jan-Mar;41(1):5-7.Conceptual and methodologic challenges of assessing the short-term efficacy of Guggulu in obesity: data emergent from a naturalistic clinical trial. J Postgrad Med 1995 Jan-Mar;41(1):5-7. Bhatt AD et al. |
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